Wrinkles are lines that has become prominent due to thousands of repetitions of the same expression. Wrinkles are also called “crow’s feet” because of their “expression lines” or shape. Wrinkles are caused by the contraction of the muscles under the skin. Botox is a purified protein toxin derived from a bacterium called “clostridium botulinum”. The reason why it is harmless is that it is used in very small doses and does not disperse into the body. This protein relaxes the muscles in the area where it is used, and enable the skin to tighten and therefore rejuvenate for a certain period of time. Botox is injected under the skin in the problematic area of the face in very small doses through tiny surgical needles. In this way, the contracted muscles begin to relax. It reaches its highest efficiency about three weeks after Botox is applied. Although the duration of Botox differs from person to person, it is about 3-6 months. It is generally recommended to repeat the procedure every 4-6 months. Applying ice to the area after Botox application reduces possible swelling or discomfort. Since the entire treatment takes about 10-15 minutes, it is possible to return to normal life immediately. However, it is recommended to wait for 4-6 hours in lying position. In order for the Botox not to disperse into the surrounding muscles, the Botox applied area should not be rubbed.